Glucosamine does not solve arthritis. Supplements and TCMs in orthopedics are like scams. Be mindful that TCM does not solve bone and joint issues, they just anyhow guess, or even inflict more pain to distract your body.
Knee Replacement surgery is the only solution. However, this is a scary operation.
In my biased opinion, there is no good orthopedic in private sector because they don't upgrade their skills for years.  I can name a few many "reputable" orthopedics in private sector who screwed up badly and patients had to go back to govt hospital to seek help. I can write another page about their dirty deeds.
You will rely on injections when your knee starts to give u problem and you must reduce your running or climbing stairs. Slow walk is fine. Be mindful that humans are more like monkeys than leopards, so you don't really see monkeys running long distances.
Knee Replacement surgeries have advanced in the past decade, and significantly reduced recovery time. You could get off your bed within 24-48 hours and walk happily within a month if you have a good doctor. In government hospitals, the young doctors are very good because they have been trained to operate robotics which provide more precision and shorten operation time (which translates to a shorter recovery). The senior doctors are like skilled craftmen because Knee Replacement surgeries pretty much rely on "worksmanship". The best senior doctors in government hospitals are so good that they end up clearly shit for the private hospital doctors eg handle re-operations, infections, or re-replacement 5-10 years later.
If you don't replace your worn knees, you will eventually injure or spoil your hips and spine, especially if you are female. Less doctors will do for you when you are 85 when you are in severe pain and spine destroyed.  By then, painkillers will not help. You cannot even move or sit upright. However, if you operate early and continue to run and climb stairs, you probably need another (re-do) before you die. Therefore, many people drag their feet.