Another new day another big pharma beat the competition to get FDA approval for new vaccine against pneumonia

[ginfreely]

https://medcitynews.com/2021/06/pfi...etting-edge-in-pneumococcus-vax-race-for-now/

Pfizer’s Prevnar 20 wins FDA nod, getting edge in pneumococcus vax race—for now​

The FDA has approved Prevnar 20, a Pfizer vaccine that protects against 20 pneumococcal strains—seven more than the company’s blockbuster Prevnar 13. But others are on the big pharma company’s heels with vaccine candidates that aim to match or even beat the Pfizer pneumococcal vaccines.​

By FRANK VINLUAN

Post a comment / Jun 9, 2021 at 10:28 AM

 

[ginfreely]

A Pfizer vaccine that addresses 20 types of pneumococcal bacteria has won FDA approval, giving the company a successor to a blockbuster product and the edge in a race to protect against more of these strains that can lead to serious infections, such as pneumonia and meningitis.

Pneumococcal infections are caused by the bacteria Streptococcus pneumoniae. There are more than 90 strains. As its name conveys, Prevnar 20 vaccine protects against 20 of these strains, improving on Prevnar 13, a Pfizer product that accounted for more than $5.8 billionin global sales last year. Approval of Prevnar 20 covers adults 18 and older.

 

[ginfreely]

Prevnar 20 is what’s called a conjugate vaccine. The antigens for the vaccine are polysaccharides, chains of sugar molecules from the bacteria’s outer coat. The polysaccharides are conjugated, or bonded, to a carrier protein. By carrying more of these polysaccharides, a vaccine can protect against more strains.

According to Pfizer, the seven additional strains covered in Prevnar 20 account for about 40% of all pneumococcal disease cases and deaths in the U.S. All 20 of the strains are estimated to be responsible for more than half of all U.S. cases of invasive pneumococcal disease, which include bacteremia and meningitis, as well as community-acquired pneumonia.

With Prevnar 20’s approval, Pfizer can claim it offers a vaccine that protects against more of the disease-causing pneumococcal strains than any other vaccine currently available. However, competition is on the way. Though Merck’s V114 protects against five fewer pneumococcal strains than Prevnar 20, the pharmaceutical giant is further along in clinical testing of its candidate in children. Last month, Merck reported positive preliminary results of a Phase 3 pediatric test of its vaccine. An FDA decision on V114 in adults is expected in mid-July.

 

[ginfreely]

Other companies are in earlier stages with their pneumococcal vaccines. The lead candidate of Vaxcyte is VAX-24, a pneumococcal vaccine candidate designed to protect against 24 strains. The Foster City, California-based biotech is in preclinical development with VAX-24. The lead candidate of Affinivax also addresses 24 pneumococcal strains. The Cambridge, Massachusetts-based startup has advanced that candidate, ASP3772, through Phase 2 testing under a collaboration with pharmaceutical company Astellas. That vaccine candidate is also in Phase 1 testing in toddlers.

Prevnar 20 was submitted to the European Medicines Agency in February. That review is ongoing. Following the FDA approval of Prevnar 20, Pfizer said that the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices is expected to meet in October to discuss and update its recommendations on the safe and appropriate use of pneumococcal vaccines in adults.

 

[lostvirgin]

Darling, I vaccinated you against rabies when you were young. It works?

 

[Leongsam]

All these vaccines do is keep you alive so that you can die of cancer instead.

 

[Scrooball (clone)]

All these vaccines do is keep you alive so that you can die of cancer instead.

U do know that everyone have cancer cells in their bodies right? Try reading science books instead of visiting conspiracy theories websites.

 

[Leongsam]

U do know that everyone have cancer cells in their bodies right? Try reading science books instead of visiting conspiracy theories websites.

My point exactly. Throughout out lives the there are cells that do not divide according to plan and go rouge. These abnormal cells are identified and dealt with by the body's internal defenses. However there will be a point in time when a dysplasic cell is missed and this is how the seed of cancer is planted.

The older we are the more likely it is that this will happen.

What exactly have I said that sounds like a conspiracy theory?

 

[ginfreely]

All these vaccines do is keep you alive so that you can die of cancer instead.

Maybe these vaccines could have prevented my lung infection last year.

 

[Scrooball (clone)]

Maybe these vaccines could have prevented my lung infection last year.

Stop swallowing cum for a month or two and your lungs should clear up just fine.

 

[ginfreely]

Stop swallowing cum for a month or two and your lungs should clear up just fine.

Sia suay loser evil filthy coward liar sons of whores like you that twist all my illness to sex related should burn to death and burn in hell forever. So scared to die dare not swear if i am not what you said you be burnt to death. Pui!

 

[ginfreely]

Stop swallowing cum for a month or two and your lungs should clear up just fine.

And look at the evil filthy fakes @empathizerofeatshitndie @sweetiepie that like such horrible lies while accusing others a liar

 

[ginfreely]

U do know that everyone have cancer cells in their bodies right? Try reading science books instead of visiting conspiracy theories websites.

I hope you have lung nodules in your lungs - just like me - and they grow bigger to become cancer while mine remain as they are. Pui!

 

[ginfreely]

I hope you have lung nodules in your lungs - just like me - and they grow bigger to become cancer while mine remain as they are. Pui!

As usual I am 0.01% Singaporean non smoker non everything to have lung scarring and lung nodules.

 

[ginfreely]

As usual I am 0.01% Singaporean non smoker non everything to have lung scarring and lung nodules.

But as usual heaven will always bless me when it comes to the crunch.

 

[ginfreely]

And look at the evil filthy fakes @empathizerofeatshitndie @sweetiepie that like such horrible lies while accusing others a liar

@empathizerofeatshitndie quickly and proudly post the evil filthy shit post to classic forum replies thread that i am locked out of posting by his fellow snake @zhihau.

 

[ginfreely]

@empathizerofeatshitndie quickly and proudly post the evil filthy shit post to classic forum replies thread that i am locked out of posting by his fellow snake @zhihau.

@Leongsam @zhihau @Froggy please unlock this thread to enable me to reply there. Now I only can like the post, cannot post.

 

[capamerica]

All these vaccines do is keep you alive so that you can die of cancer instead.

Another stupid opinion which is ironic since mRNA therapies are used to treat cancer.

Do you know anything ?

Or just plain stupid?

 

[capamerica]

My point exactly. Throughout out lives the there are cells that do not divide according to plan and go rouge. These abnormal cells are identified and dealt with by the body's internal defenses. However there will be a point in time when a dysplasic cell is missed and this is how the seed of cancer is planted.

The older we are the more likely it is that this will happen.

What exactly have I said that sounds like a conspiracy theory?

You run a conspiracy theory Shit Times forum

talking about neoplasia is a natural context does not absolve you from your stupidity

 

[republicunt]

All these vaccines do is keep you alive so that you can die of cancer instead.

U r very idiot person