From a practical standpoint, vaxxing pass ports are bee cumings a reality so if you want travel you need to show proof of vaxxing nation. Yous need reliable one else your world most powder full pass port is good as use less with out it. Where sinovac places in efficacy now and later remains to be seen.
That why u r goondu idiot
What kind of "gene therapy" are you referring to? If you are thinking mRNA vaccines are a form of gene therapy that will alter your DNA in some way, then sorry to disappoint you. They don't. The mRNA molecules, which are short-lived, don't affect or interact with our DNA because they don't even enter the nucleus of cells where the DNA is stored.
For all the damage they may cause, you are still eating a whole lot of GMO food, meats and poultry injected with growth hormones, the long term effects of which are not fully explored. What is a few more weird proteins injected in to your body?
No. Sinovac is an inactivated vaccine. Mordena and Pfizer are mRNA vaccines. One is a traditional vaccine using killed viral particles to expose the body's immune system and the other uses genetic codes to train the immune system to attack. Both are proven to be effective.
What kind of "gene therapy" are you referring to? If you are thinking mRNA vaccines are a form of gene therapy that will alter your DNA in some way, then sorry to disappoint you. They don't. The mRNA molecules, which are short-lived, don't affect or interact with our DNA because they don't even enter the nucleus of cells where the DNA is stored.
Go read up more in-depth of the technology that goes into the making of the vaccine. You'll be fascinated by the advancements made in medical science.
A gene is a region of DNA that encodes function. A chromosome consists of a long strand of DNA containing many genes. A human chromosome can have up to 500 million base pairs of DNA with thousands of genes. |
Nobody took issue with describing mRNA as a form of "gene therapy" prior to 2020 as the article below clearly illustrates.
It was only when mRNA vaccines burst onto the scene with the potential for untold riches for many that "experts" suddenly became pedantic over the use of the term.
mRNA therapy: A new form of gene medicine
https://medium.com/@hareth.wassiti?source=post_page-----5d859dadd1e--------------------------------
Harry Al-Wassiti
Dec 11, 2019 · 5 min read
View attachment 112811
It has been several weeks since I came back from Berlin. I was visiting the international mRNA health conference, where I presented our latest development in the mRNA therapy field. Unlike the USA and Europe, mRNA research in Australia is still a young concept. As far as we know, we are probably one of the only groups in Australia who are actively working on mRNA therapy. On my way back to Australia thinking of all the great discoveries I just witnessed in the conference- I had a thought. I must write about mRNA therapy, so more people can know about it. Because when mRNA therapy reaches its age, it will touch most of us.
So what are mRNA and gene therapies and how do they work?
To understand this new class of therapies, we must first understand what makes up mRNA and gene therapies. These molecules are known as nucleic acids. In our cells, there are two major types of nucleic acid molecules: Genomic DNA and mRNA. These carry the manual for all the instructions your cells and body need. They are the code for life. The basic principle of traditional gene therapy is to insert or add a DNA molecule, with specific “designed” instructions and is “translated” by your cell as a protein. In the case of gene therapy, it treats people who lack that protein. mRNA, also known as messenger RNA, is naturally found in all our cells. mRNA is responsible for carrying out a message from the DNA that lies inside the nucleus to the cytoplasm. In there, the proteins are made from the mRNA sequence in a process known as translation. So mRNA therapy uses mRNA molecules instead of DNA molecules, thereby bypassing the need for DNA and simplifying the process (See the figure below).
Nucleic acid therapy, whether it is derived from mRNA or DNA, is a transformational concept in medicine. In contrast to conventional drugs- small molecules acting on a protein or a “target” inside your body- nucleic acid therapy instead instruct your body to make or break the proteins inside your cells at a more fundamental level. You could imagine your DNA and mRNA as the operating program system (OS) for life. Much like computer OS, mRNA therapy can reprogram your body to produce its own therapies. An intriguing concept, indeed.
And what are the uses of mRNA therapy?
Back to Berlin’s conference, many academic and biotech groups presented a wide range of medical applications using mRNA. We and others have envisaged, many times, the range of applications mRNA therapy can have.
Given the mRNA inherent “programmability”, it’s relatively easy to adjust the sequence of mRNA to make, theoretically, any therapeutic protein. This means it can cover a wide range of diseases. Examples of applications that have gone into clinical trials (i.e. trialled in a small number of humans) are cancer immunotherapy, viral vaccines and enzyme replacement therapy for the liver. But the list, as we all expect, won’t stop here. In the context of the human application, many groups and biotech companies presented impressive findings, but these results are still early.
Why is Biotech building mRNA tech?
Effectiveness: Conventional DNA gene therapy needs to overcome many challenges before it becomes a therapeutically viable option. For DNA gene therapy to be active, it requires to reach not only the cell but the very nucleus inside that cell. This is an incredibly difficult task given that our nuclei have evolved to prevent any foreign DNA from entering (Think viruses!). While mRNA therapy shares some of the difficulties of traditional gene therapy, it requires to reach only the cytoplasm of the cells, not the nucleus. Arguably, this is a simpler technical challenge compared to DNA therapy.
https://en.wikipedia.org/wiki/Gene
From Wikipedia, the free encyclopedia
This article is about the heritable unit for transmission of biological traits. For other uses, see Gene (disambiguation).
In biology, a gene (from genos [1] (Greek) meaning generation[2] or birth [1] or gender) is a basic unit of heredity and a sequence of nucleotides in DNA or RNA that encodes the synthesis of a gene product, either RNA or protein.[3][4][5]
A gene is a region of DNA that encodes function. A chromosome consists of a long strand of DNA containing many genes. A human chromosome can have up to 500 million base pairs of DNA with thousands of genes.
During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA
sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or the number of limbs, and some are not, such as blood type, the risk for specific diseases, or the thousands of basic biochemical processes that constitute life.
And from Pfizer's coffers to whose pockets?
Yes, appreciate your "gene medicine" posting. And what's your point?Nobody took issue with describing mRNA as a form of "gene therapy" prior to 2020 as the article below clearly illustrates.
It was only when mRNA vaccines burst onto the scene with the potential for untold riches for many that "experts" suddenly became pedantic over the use of the term.
mRNA therapy: A new form of gene medicine
https://medium.com/@hareth.wassiti?source=post_page-----5d859dadd1e--------------------------------
Harry Al-Wassiti
Dec 11, 2019 · 5 min read
View attachment 112811
It has been several weeks since I came back from Berlin. I was visiting the international mRNA health conference, where I presented our latest development in the mRNA therapy field. Unlike the USA and Europe, mRNA research in Australia is still a young concept. As far as we know, we are probably one of the only groups in Australia who are actively working on mRNA therapy. On my way back to Australia thinking of all the great discoveries I just witnessed in the conference- I had a thought. I must write about mRNA therapy, so more people can know about it. Because when mRNA therapy reaches its age, it will touch most of us.
So what are mRNA and gene therapies and how do they work?
To understand this new class of therapies, we must first understand what makes up mRNA and gene therapies. These molecules are known as nucleic acids. In our cells, there are two major types of nucleic acid molecules: Genomic DNA and mRNA. These carry the manual for all the instructions your cells and body need. They are the code for life. The basic principle of traditional gene therapy is to insert or add a DNA molecule, with specific “designed” instructions and is “translated” by your cell as a protein. In the case of gene therapy, it treats people who lack that protein. mRNA, also known as messenger RNA, is naturally found in all our cells. mRNA is responsible for carrying out a message from the DNA that lies inside the nucleus to the cytoplasm. In there, the proteins are made from the mRNA sequence in a process known as translation. So mRNA therapy uses mRNA molecules instead of DNA molecules, thereby bypassing the need for DNA and simplifying the process (See the figure below).
Nucleic acid therapy, whether it is derived from mRNA or DNA, is a transformational concept in medicine. In contrast to conventional drugs- small molecules acting on a protein or a “target” inside your body- nucleic acid therapy instead instruct your body to make or break the proteins inside your cells at a more fundamental level. You could imagine your DNA and mRNA as the operating program system (OS) for life. Much like computer OS, mRNA therapy can reprogram your body to produce its own therapies. An intriguing concept, indeed.
And what are the uses of mRNA therapy?
Back to Berlin’s conference, many academic and biotech groups presented a wide range of medical applications using mRNA. We and others have envisaged, many times, the range of applications mRNA therapy can have.
Given the mRNA inherent “programmability”, it’s relatively easy to adjust the sequence of mRNA to make, theoretically, any therapeutic protein. This means it can cover a wide range of diseases. Examples of applications that have gone into clinical trials (i.e. trialled in a small number of humans) are cancer immunotherapy, viral vaccines and enzyme replacement therapy for the liver. But the list, as we all expect, won’t stop here. In the context of the human application, many groups and biotech companies presented impressive findings, but these results are still early.
Why is Biotech building mRNA tech?
Effectiveness: Conventional DNA gene therapy needs to overcome many challenges before it becomes a therapeutically viable option. For DNA gene therapy to be active, it requires to reach not only the cell but the very nucleus inside that cell. This is an incredibly difficult task given that our nuclei have evolved to prevent any foreign DNA from entering (Think viruses!). While mRNA therapy shares some of the difficulties of traditional gene therapy, it requires to reach only the cytoplasm of the cells, not the nucleus. Arguably, this is a simpler technical challenge compared to DNA therapy.
Ok... so?https://en.wikipedia.org/wiki/Gene
From Wikipedia, the free encyclopedia
This article is about the heritable unit for transmission of biological traits. For other uses, see Gene (disambiguation).
In biology, a gene (from genos [1] (Greek) meaning generation[2] or birth [1] or gender) is a basic unit of heredity and a sequence of nucleotides in DNA or RNA that encodes the synthesis of a gene product, either RNA or protein.[3][4][5]
A gene is a region of DNA that encodes function. A chromosome consists of a long strand of DNA containing many genes. A human chromosome can have up to 500 million base pairs of DNA with thousands of genes.
During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA
sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or the number of limbs, and some are not, such as blood type, the risk for specific diseases, or the thousands of basic biochemical processes that constitute life.
Ok. So gene therapy is a field of study. I think what concerns people most about gene therapy and mRNA vaccines is whether it alters DNA. It doesn't.The point is that just because mRNA does not alter your DNA does not mean it is not a form of gene therapy.
