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The Pfizer vaccine is slightly less effective but appears to still protect against the more transmissible Indian strain of the virus that causes COVID-19, according to a study by France’s Pasteur Institute.
“Despite slightly diminished efficacy, the Pfizer vaccine probably protects” against the Indian variant, according to laboratory test results, said Olivier Schwartz, the institute’s director and co-author of the study that was published on the BioRxiv website ahead of peer review.
The study sampled 28 health care workers in the city of Orleans. Sixteen of them had received two doses of the Pfizer vaccine, while 12 had received one dose of the AstraZeneca vaccine.
People who had received two doses of Pfizer saw a threefold reduction in their antibodies against the Indian variant, B.1.617, according to the study, but were still protected.
“The situation was different with the AstraZeneca vaccine, which induced particularly low levels of antibodies neutralizing” the Indian variant, the study said.
Patients who had had COVID-19 within the past year and people vaccinated with two doses of Pfizer retained enough antibodies to be protected against the Indian variant, but three to six times less antibodies than against the U.K. variant, Schwartz said.
The study shows that “this variant … has acquired partial resistance to antibodies,” Schwartz said.
Since first emerging in late 2019 in China, the SARS-CoV-2 virus that causes COVID-19 has developed several variants, usually named for the places where it first appeared including the so-called South Africa and U.K. strains.
The variant first detected in India appears to be much more transmissible than earlier variations.
It has now been officially recorded in 53 territories, according to a World Health Organization report.
To try to curb its spread, Japan has re-introduced tighter rules on arrivals from countries where the variant is spreading, including India, Nepal and Sri Lanka.
France and Germany have also tightened rules on arrivals from affected countries, including the United Kingdom.
www.japantimes.co.jp
“Despite slightly diminished efficacy, the Pfizer vaccine probably protects” against the Indian variant, according to laboratory test results, said Olivier Schwartz, the institute’s director and co-author of the study that was published on the BioRxiv website ahead of peer review.
The study sampled 28 health care workers in the city of Orleans. Sixteen of them had received two doses of the Pfizer vaccine, while 12 had received one dose of the AstraZeneca vaccine.
People who had received two doses of Pfizer saw a threefold reduction in their antibodies against the Indian variant, B.1.617, according to the study, but were still protected.
“The situation was different with the AstraZeneca vaccine, which induced particularly low levels of antibodies neutralizing” the Indian variant, the study said.
Patients who had had COVID-19 within the past year and people vaccinated with two doses of Pfizer retained enough antibodies to be protected against the Indian variant, but three to six times less antibodies than against the U.K. variant, Schwartz said.
The study shows that “this variant … has acquired partial resistance to antibodies,” Schwartz said.
Since first emerging in late 2019 in China, the SARS-CoV-2 virus that causes COVID-19 has developed several variants, usually named for the places where it first appeared including the so-called South Africa and U.K. strains.
The variant first detected in India appears to be much more transmissible than earlier variations.
It has now been officially recorded in 53 territories, according to a World Health Organization report.
To try to curb its spread, Japan has re-introduced tighter rules on arrivals from countries where the variant is spreading, including India, Nepal and Sri Lanka.
France and Germany have also tightened rules on arrivals from affected countries, including the United Kingdom.
Pfizer jab less effective but still protects against Indian strain, study finds
"Despite slightly diminished efficacy, the Pfizer vaccine probably protects" against the Indian variant, according to laboratory test results.
