It's not a Chinese virus you fools!

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Cambridge scientist suggests virus did not originate in Wuhan
685873.jpg

Getting tested: Residents wearing face masks lining up for nucleic acid testing at a residential compound in Wuhan. — Reuters
BEIJING: There is strong evidence that SARS-Cov-2, or the novel coronavirus that causes Covid-19, didn’t originate in the city of Wuhan, a University of Cambridge geneticist has found.
In a recent paper published in the journal Proceedings of the National Academy of Sciences of the USA, Peter Forster, a fellow in archaeological research at Cambridge, said he found three main strains of the virus, labelled as A, B and C.


The A and C types are found in significant proportions outside East Asia, that is, in Europeans and Americans.
In contrast, the B type is the most common type in East Asia.

The A strain was the founding variant because it was the version most similar to the type of SARS-Cov-2 discovered in bats, but it wasn’t the predominant type in Wuhan, according to his research.
Of 23 samples that came from Wuhan, only three were type A, the rest were type B, a version two mutations from A.
But in other parts of China, initially A was the predominant strain, the research said. For instance, of nine genome samples in Guangdong province, five were the A strain.
The A type has largely phased out, and the B type has become the predominant version. The C strain, which mainly appeared in Singapore, South Korea, Hong Kong and in some parts of Europe, has also largely died out.
His research also found that the coronavirus may have been circulating among humans and animals earlier than previously believed, based on an analysis of the mutation rate.
He found that there is a 95% chance that the original successful spread of the virus may have started as early as Sept 13,2019. Covid-19 was first reported in Wuhan in December. — China Daily/ANN
 
it is important to understand where the virus is originated, not because to point finger but to able to find out the root caused to prevent future pandemic.
Wish all specialist and head of nation can understand this, its year 2020, we have speak of world peace and now we are not better than cave man when come to world harmony
 
Cambridge scientist suggests virus did not originate in Wuhan
  • CHINA
  • Monday, 18 May 2020
685873.jpg

Getting tested: Residents wearing face masks lining up for nucleic acid testing at a residential compound in Wuhan. — Reuters
BEIJING: There is strong evidence that SARS-Cov-2, or the novel coronavirus that causes Covid-19, didn’t originate in the city of Wuhan, a University of Cambridge geneticist has found.
In a recent paper published in the journal Proceedings of the National Academy of Sciences of the USA, Peter Forster, a fellow in archaeological research at Cambridge, said he found three main strains of the virus, labelled as A, B and C.


The A and C types are found in significant proportions outside East Asia, that is, in Europeans and Americans.
In contrast, the B type is the most common type in East Asia.

The A strain was the founding variant because it was the version most similar to the type of SARS-Cov-2 discovered in bats, but it wasn’t the predominant type in Wuhan, according to his research.
Of 23 samples that came from Wuhan, only three were type A, the rest were type B, a version two mutations from A.
But in other parts of China, initially A was the predominant strain, the research said. For instance, of nine genome samples in Guangdong province, five were the A strain.
The A type has largely phased out, and the B type has become the predominant version. The C strain, which mainly appeared in Singapore, South Korea, Hong Kong and in some parts of Europe, has also largely died out.
His research also found that the coronavirus may have been circulating among humans and animals earlier than previously believed, based on an analysis of the mutation rate.
He found that there is a 95% chance that the original successful spread of the virus may have started as early as Sept 13,2019. Covid-19 was first reported in Wuhan in December. — China Daily/ANN
China Daily is an English-language daily newspaper owned by the Publicity Department of the Communist Party of China.
 
Cambridge is in UK. The news portal merely reporting what was mentioned.here is another same report from US news.


U.S. News & World Report Homepage
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NEWS




Did the Coronavirus Originate Outside of Wuhan?
Research by a Cambridge geneticist suggests the coronavirus may have been circulating earlier than previously believed.
By Thomas K. Grose, Contributor May 13, 2020

U.S. News & World Report

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TOPSHOT - A medical staff member gestures inside an isolation ward at Red Cross Hospital in Wuhan in China's central Hubei province on March 10, 2020. - Chinese President Xi Jinping said on March 10 that Wuhan has turned the tide against the deadly coronavirus outbreak, as he paid his first visit to the city at the heart of the global epidemic. (Photo by STR / AFP) / China OUT (Photo by STR/AFP via Getty Images)

A medical staff member gestures inside an isolation ward at Red Cross Hospital in Wuhan in China's central Hubei province on March 10, 2020.(STR/AFP VIA GETTY IMAGES)
LONDON – THERE'S NO doubt that the novel coronavirus that causes COVID-19, the highly contagious disease that's so far infected more than 4.2 million people globally and killed nearly 290,000, originated in China.
But while early analyses of the outbreak indicated that it first emerged in humans in the city of Wuhan — which became the epicenter of China's epidemic — possibly at a seafood market, that scenario hasn't been fully confirmed by researchers.

Now a University of Cambridge geneticist says there is strong circumstantial evidence that the virus didn't originate in Wuhan after all.
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"This idea that the Wuhan seafood market is the origin is actually not clear-cut," says Peter Forster, a fellow in archaeological research at Cambridge.
If Forster's research holds up, it would also put to rest a dubious claim made by U.S. President Donald Trump and Mike Pompeo, the secretary of state, that the pathogen leaked from the Wuhan Institute of Virology, a government lab. Neither Trump nor Pompeo has offered evidence to back up that assertion, and the intelligence agencies of America's closest allies have debunked it.
Forster is a co-inventor of phylogenetic algorithms that have, since the 1990s, become the standard software for mining genetic data to reconstruct human evolutionary trees, or networks. His team applied the software to 44 genome samples of the coronavirus gleaned from the earliest official reported cases in China from Dec. 24 of last year to Jan. 17.
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In a recent paper published in the journal Proceedings of the National Academy of Sciences, Forster reported he found three main strains of the virus that he labeled A, B and C.
His research determined that A was the founding variant because it was the version most similar to the type of SARS-Cov-2 (the scientific name for the virus) discovered in bats. Many experts suspect that the virus migrated to humans from bats, probably via some other animal. But he also discovered that the A strain wasn't the predominant type in Wuhan.

Of 23 samples that came from Wuhan, only three were type A, the rest were type B, a version two mutations from A. But in other parts of China, Forster says, initially A was the predominant strain. For instance, of nine genome samples in Guangdong, some 600 miles south of Wuhan, five were A types.
"I would be a bit careful about pinpointing a place (of origin), because we don't have many samples from the early phase," he says. "But it seems to me we shouldn't restrict ourselves to Wuhan when looking for the origin."
Asked if his ongoing research should quash speculation that the virus leaked from the Wuhan lab, Forster is circumspect. "It's not black and white. All I can say is it doesn't look to me as if Wuhan is the prime candidate, because A exists in other regions of China at that time at possibly a higher frequency."
The B type has since become the predominant version. The A type has largely petered out, as has the third variant, C, which mainly took hold in Singapore, South Korea, Hong Kong and in scattered areas around Europe.
Forster's research also indicates that COVID-19 may have been circulating among humans and animals before the reported first case in China on Dec. 1. The mutation rate he used indicates that there is a 95% chance that the original successful spread of the virus may have commenced as far back as Sept. 13, 2019.
However, he adds, that assumes "that the mutation rate is constant and that I can simply use it as a clock to go back in time." Since then, however, he's now analyzed 1,001 virus genomes, and has determined that while the mutation rate in East Asia is around 1.5 per month, outside that region it's closer to 2 or 2.1 per month.

"It's clear that the virus can change its mutation rate," Forster explains. "And if that has happened now, it might also have happened in the past, and in that case we can't be sure whether my estimate is accurate. But I would say it's the best we can do at the moment."
The B type's rapid mutation rate also doesn't look like neutral evolution, he says, and it may be affected by some form of natural selection in response to environmental influences. "The virus seems to have accelerated outside East Asia, and this is in keeping with the odd appearance of the B type."
That finding also seems to be in line with research last week out of the Los Alamos National Laboratory that found that the current dominant strain of the coronavirus appears to be more contagious than other strains.
Ian Lipkin, a virologist at Columbia University, is working with Chinese researchers to investigate hospital samples in China to see if there is more evidence that the outbreak occurred elsewhere in China before it was picked up in Wuhan. "He is conducting the kind of work my research is pointing at," Forster says.
Determining the exact origins of a lethal virus is an important step in trying to stop future outbreaks of similar pathogens, which is why Lipkin and virologists -- some guided by roadmaps like Forster's genetic family trees -- are making a concerted effort to pinpoint COVID-19's origins. And chances are good that they'll eventually solve the mystery.
 
China Daily is an English-language daily newspaper owned by the Publicity Department of the Communist Party of China.

And we know how scientists and politicians can be bought with Chinese grant money.
 
Ok. Here us the real deal right ftom Cambridge itself. But a bit dated by 15 days,

COVID-19: genetic network analysis provides ‘snapshot’ of pandemic origins
Figure from the PNAS paper showing the transmission routes using phylogenetic networks


Study charts the 'incipient supernova' of SARS-CoV-2 through genetic mutations as it spread from China and Asia to Australia, Europe and North America. Researchers say their methods could be used to help identify undocumented infection sources.


Phylogenetic network analysis has the potential to help identify undocumented COVID-19 infection sources
Peter Forster
UPDATED on Thursday April 30th 2020 with the following statement from Dr Peter Forster: "Our analysis published in the Proceedings of the National Academy of Sciences (PNAS) looked at the early spread of the virus in humans. Our analysis was not designed to investigate rumours suggesting the virus itself came from outside China. It is a misinterpretation of our research to suggest that the novel coronavirus originated outside China."

Researchers from Cambridge, UK, and Germany have reconstructed the early 'evolutionary paths' of SARS-CoV-2 in humans – as infection spread from Wuhan out to Europe and North America – using genetic network techniques.'
By analysing the first 160 complete virus genomes to be sequenced from human patients, the scientists have mapped some of the original spread of the new coronavirus through its mutations, which creates different viral lineages.
“There are too many rapid mutations to neatly trace a SARS-CoV-2 family tree. We used a mathematical network algorithm to visualise all the plausible trees simultaneously,” said geneticist Dr Peter Forster, lead author from the University of Cambridge.
“These techniques are mostly known for mapping the movements of prehistoric human populations through DNA. We think this is one of the first times they have been used to trace the infection routes of a coronavirus like COVID-19.”
The team used data from virus genomes sampled from across the world between 24 December 2019 and 4 March 2020. The research revealed three distinct 'variants' of SARS-CoV-2, consisting of clusters of closely related lineages, which they label ‘A’, ‘B’ and ‘C’.
Forster and colleagues found that the closest type of SARS-CoV-2 to the one discovered in bats – type ‘A’, the “original human virus genome” – was present in Wuhan, but surprisingly was not the city’s predominant virus type.
Versions of ‘A’ were seen in Chinese individuals, and Americans reported to have lived in Wuhan, and mutated versions of ‘A’ were found in patients from the USA and Australia.
Wuhan’s major virus type, ‘B’, was prevalent in patients from across East Asia. However, the variant didn’t travel much beyond the region without further mutations – implying a 'founder event' in Wuhan, or 'resistance' against this type of coronavirus outside East Asia, say researchers.
The ‘C’ variant is the major European type, found in early patients from France, Italy, Sweden and England. It is absent from the study’s Chinese mainland sample, but seen in Singapore, Hong Kong and South Korea.
The new analysis also suggests that one of the earliest introductions of the virus into Italy came via the first documented German infection on 27 January, and that another early Italian infection route was related to a 'Singapore cluster'.
Importantly, the researchers say that their genetic networking techniques accurately traced established infection routes: the mutations and viral lineages joined the dots between known cases.
As such, the scientists argue that these 'phylogenetic' methods could be applied to the very latest coronavirus genome sequencing to help predict future global hot spots of disease transmission and surge.
“Phylogenetic network analysis has the potential to help identify undocumented COVID-19 infection sources, which can then be quarantined to contain further spread of the disease worldwide,” said Forster, a fellow of the McDonald Institute of Archaeological Research at Cambridge, as well as the University’s Institute of Continuing Education.
The findings are published today in the journal Proceedings of the National Academy of Sciences (PNAS). The software used in the study, as well as classifications for over 1,000 coronavirus genomes and counting, is available free at www.fluxus-technology.com.
Variant ‘A’, most closely related to the virus found in both bats and pangolins, is described as 'the root of the outbreak' by researchers. Type ‘B’ is derived from ‘A’, separated by two mutations, then ‘C’ is in turn a “daughter” of ‘B’.
Researchers say the localisation of the ‘B’ variant to East Asia could result from a 'founder effect': a genetic bottleneck that occurs when, in the case of a virus, a new type is established from a small, isolated group of infections.
Forster argues that there is another explanation worth considering. “The Wuhan B-type virus could be immunologically or environmentally adapted to a large section of the East Asian population. It may need to mutate to overcome resistance outside East Asia. We seem to see a slower mutation rate in East Asia than elsewhere, in this initial phase.”
He added: “The viral network we have detailed is a snapshot of the early stages of an epidemic, before the evolutionary paths of COVID-19 become obscured by vast numbers of mutations. It’s like catching an incipient supernova in the act.”
Since today’s PNAS study was conducted, the research team has extended its analysis to 1,001 viral genomes. While yet to be peer-reviewed, Forster says the latest work suggests that the first infection and spread among humans of SARS-CoV-2 occurred between mid-September and early December.
The phylogenetic network methods used by researchers – allowing the visualisation of hundreds of evolutionary trees simultaneously in one simple graph – were pioneered in New Zealand in 1979, then developed by German mathematicians in the 1990s.
These techniques came to the attention of archaeologist Professor Colin Renfrew, a co-author of the new PNAS study, in 1998. Renfrew went on to establish one of the first archaeogenetics research groups in the world at the University of Cambridge.
 
Cambridge also said the virus will kill millions forcing the gahmens to implement lockdowns n fucking up the economy. Their statements are worth fuckall
 
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