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Sodium dichloracetate is an agent that lowers the energy level of the cancer cells, making them more sensitive to other cancer fighting approaches. In addition it invades the cancer cells and promotes their programmed cell death.
The ketogenic diet at Esperance uses modified techniques and monitoring to ensure safety and minimize loss of muscle mass. The diet can lower the energy levels of the cancer cells, as well as kill them directly because the ketone bodies produced through this diet are toxic to many cancer cells. Furthermore, it can potentially play a huge role in frailty prevention that is often experienced by cancer patients.
Cancer growth and many cancer features are driven by a lack of oxygen in the body. Therefore, exposure to hyperbaric oxygen can reverse many hallmarks of cancer. Secondly, HBO has the ability to directly kill cancer cells. HBO also potentiates other types of cancer treatments, such as chemotherapy, radiotherapy, laser, hyperthermia and immunotherapy, and contributes to the patient’s quality of life by reducing cancer related fatigue.
As cancer thrives in an acidic environment, alkalinizing a tumor’s micro-environment using multiple modalities can decrease the cancer’s ability to replicate and metastasize.
Ketogenic metabolic therapy, using calorie-restricted high fat, low carbohydrate ketogenic diets, is a therapeutic strategy that can be effective for starving cancer cells. This approach shifts the body away from using glucose to using ketone bodiesand fats for energy, thus starving cancer cells of their prime fermentable fuel. The dependency of tumor cells on glucose has become known as the Warburg effect, in recognition of Otto Warburg who first described cancer as a disease of mitochondrial energy metabolism. As ketone bodies and fats are nonfermentable, these fuels are accessible only to normal cells, which contain normal mitochondrial function. We found that ketogenic metabolic therapy used with drugsthat also target glutamine can be effective in managing advanced-stage brain cancer. The key is to simultaneously restrict availability of both glucose and glutamine. As most if not all cancers depend on glucose and glutamine fermentation for survival, this therapeutic starvation strategy should be effective in managing most if not all cancers.
We found that ketogenic metabolic therapy used with drugsthat also target glutamine can be effective in managing advanced-stage brain cancer. The key is to simultaneously restrict availability of both glucose and glutamine.