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UK: Triple mutant' Covid variant with 'strange gene' combination identified

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Source: https://www.mirror.co.uk/news/uk-news/triple-mutant-covid-variant-identified-24161494

Triple mutant' Covid variant identified in the UK with 'strange gene combination

Public Health England is investigating the new variant with 49 cases found so far mainly in Yorkshire and Humber while people are being told not to be alarmed by it.

By
Tim Hanlon
  • 04:06, 22 MAY 2021
  • UPDATED10:02, 22 MAY 2021

A “triple mutant” Covid variant with a “strange combination” of genes is being probed by UK virologists as England’s R rate worryingly rises to potentially over one.

There have been 49 cases found so far of the new variant mainly in Yorkshire and Humber with people being told not to be alarmed by it.


The mutant form of Covid is a “variant under investigation” but there is no evidence yet to say it is more transmissible or resistant to vaccines.

At the same time, the government has said that the Covid R rate is now somewhere between 0.9 and 1.1 which is the highest it has been since the second wave peak back in January.


Ministers have said that they will put in place any measures necessary to tackle any fresh variants.

But Greg Fell, Sheffield’s director of public health said there is no reason to think the “triple mutant variant” is more transmissible or vaccine resistant.

He said in a statement: “Please don't be alarmed, we want you to continue doing what you have been for the past year. Follow the guidance, continue to wash your hands regularly and wear a mask indoors.”

He added that where cases have been found “contact tracing and targeted testing” would be used to limit its spread, while the "strange combination of mutations" continues to be probed.

The Prime Minister's official spokesman said: 'There have been a number of variants throughout the pandemic and there will continue to be so.

0_The-Duke-Of-Cambridge-Visits-Oxford-Vaccine-Group.jpg

So far 49 cases of the new triple mutant variant have been found (Image: Getty Images)

There are three mutations of the B1617 (Indian) strain, as I think has been discussed previously, but as we do with all variants where we spot and identify them through our genomic sequencing programme, we will continue to monitor them and we will designate them as variants under investigation, and then variants of concern if we deem them to be of greater risk.

“But again, as you've seen throughout the pandemic, that's what we've done and we won't hesitate to put in measures that we think are necessary to try and tackle the transmission of any variants.”

The Office for National Statistics has estimated that it is seeing a “potential increase” in Covid cases with almost 50,000 people infected by the virus on any day last week.

But Public Health England’s weekly report found that cases had dropped in every region but the North West and in every age group bar five to nine year-olds.

Cases of the Indian variant are only surging in three areas - Bolton, Blackburn and Bedford - of the 23 hotspots which also suggests that it is not heading out of control.

Similarly, King’s College London analysis found that 2,750 people had developed Covid symptoms over the past week which is little change from the previous seven days.
 
The vaccine work...so why worry?

Two COVID-19 shots effective against B16172 variant from India: English health body
FILE PHOTO: A phial of the Pfizer/BioNTech COVID-19 vaccine concentrate is diluted with 1.8ml sodiu
FILE PHOTO: A phial of the Pfizer/BioNTech COVID-19 vaccine concentrate is diluted with 1.8ml sodium chloride ready for use at Guy's Hospital. Victoria Jones/Pool via REUTERS/File Photo
23 May 2021 05:49AM
(Updated: 23 May 2021 07:07AM)
Bookmark
LONDON: A double dose of COVID-19 vaccines is almost as effective against the fast-spreading variant of the coronavirus first identified in India as it is against Britain's dominant strain, English health officials said on Saturday (May 22).

Britain's health minister said the data was groundbreaking and he was increasingly hopeful that the government would be able to lift more COVID restrictions next month.

A study by Public Health England found the Pfizer-BioNTech vaccine was 88 per cent effective against symptomatic disease from the B16172 variant two weeks after the second dose.

That compared with 93 per cent effectiveness against the B117 "Kent" strain which is Britain's dominant COVID variant.

Two doses of the AstraZeneca vaccine were 60 per cent effective against symptomatic disease from the Indian variant compared with 66 per cent effectiveness against the Kent variant, PHE said.

"I'm increasingly confident that we're on track for the roadmap, because this data shows that the vaccine, after two doses, works just as effectively (against the Indian variant)," Health Secretary Matt Hancock told broadcasters.

Under the government's plans, a lifting of remaining coronavirus restrictions is due to take place from Jun 21.

Britain has rushed out Europe's fastest vaccination programme so far but it has faced a new challenge from the spread of the variant first found in India.

Data published on Saturday showed new COVID cases reported in Britain rose by 10.5 per cent in the seven days to May 22 although it remained a fraction of levels seen earlier this year.

Prime Minister Boris Johnson this month ordered an acceleration of remaining second doses to the over 50s and people who are clinically vulnerable.

PHE said a first dose of both vaccines was 33 per cent effective against symptomatic disease from B16172 after three weeks, lower than its 50 per cent effectiveness against B117.

Hancock said that showed that getting both doses of the vaccine was "absolutely vital."

Concern about rising cases in Britain of the variant first found in India prompted Germany to say on Friday that anyone entering the country from the United Kingdom would have to quarantine for two weeks on arrival.

Also on Friday, the head of Germany's public health institute said existing COVID-19 vaccines might be less effective against the B16172 variant.
 
Indian variant which became South Asian double variant is losing traction. The latest is now "triple" variant. :roflmao:

Be prepared for quadruple variant next week and quintuple variant in a couple of week's time.
 
Indian variant which became South Asian double variant is losing traction. The latest is now "triple" variant. :roflmao:

Be prepared for quadruple variant next week and quintuple variant in a couple of week's time.
I am really curious. Wat would happen if the virus was allowed to spread like the Spanish flu. Would this shit be over by now? The death rate in India for the virus is not even 1%. And those that died, they died with the virus or from the virus?
 
Indian variant which became South Asian double variant is losing traction. The latest is now "triple" variant. :roflmao:

Be prepared for quadruple variant next week and quintuple variant in a couple of week's time.
now you know why they dance in groups?

indian_wedding_dance_band_playing_somewhat_funny_crazy_comic_not_hd.gif
 
Source: https://www.cnbc.com/2021/05/10/who...ariant-from-india-as-global-health-risk-.html

HEALTH AND SCIENCE

WHO classifies triple-mutant Covid variant from India as global health risk​

PUBLISHED MON, MAY 10 202111:55 AM EDT UPDATED TUE, MAY 11 20211:03 PM EDT

Berkeley Lovelace Jr.@BERKELEYJR

KEY POINTS
  • A WHO official said Monday it is reclassifying the highly contagious triple-mutant Covid variant spreading in India as a “variant of concern” at the global level.
  • Maria Van Kerkhove, the WHO’s technical lead for Covid-19, said the agency will provide more details in its situation report Tuesday.


A World Health Organization official said Monday it is reclassifying the highly contagious triple-mutant Covid variant spreading in India as a “variant of concern,” indicating that it’s become a global health threat.

Maria Van Kerkhove, the WHO’s technical lead for Covid-19, said the agency will provide more details in its weekly situation report on the pandemic Tuesday but added that the variant, known as B.1.617, has been found in preliminary studies to spread more easily than the original virus and there is some evidence it may able to evade some of the protections provided by vaccines. The shots, however, are still considered effective.


“And as such we are classifying this as a variant of concern at the global level,” she said during a press conference. “Even though there is increased transmissibility demonstrated by some preliminary studies, we need much more information about this virus variant in this lineage in all of the sub lineages, so we need more sequencing, targeted sequencing to be done.”

The WHO said last week it was closely following at least 10 coronavirus variants across the world, including the B.1.617. The variant was previously labeled a “variant of interest” as more studies were needed to completely understand its significance, Van Kerkhove said.

“What it means for anybody at home is any of the SARS-CoV-2 viruses circulating can infect you and spread and everything in that sense is of concern,” she said Monday. “So, all of us at home, no matter where we live, no matter what virus is circulating, we need to make sure that we take all of the measures at hand to prevent ourselves from getting sick.”

A variant can be labeled as “of concern” if it has been shown to be more contagious, more deadly or more resistant to current vaccines and treatments, according to the WHO.

The group issued a clarification Monday to their earlier remarks, saying that current data shows the existing Covid-19 vaccines “remain effective at preventing disease and death in people infected with this variant.”


The international organization has already designated three other variants with the classification: B.1.1.7, which was first detected in the U.K. and is the most prevalent variant currently circulating throughout the U.S.; B.1.351, first detected in South Africa, and the P.1 variant, first detected in Brazil.

B.1.617 has three sublineages, Van Kerkhove said, that will be described in the situation report Tuesday.

The variant is believed by some to be behind the latest wave of infections in India.

The country is averaging about 3,879 Covid deaths per day, according to data compiled by Johns Hopkins University, though media reports indicate the official figure is being understated. It has reported an average of about 391,000 new cases per day over the past seven days — up about 4% from a week ago, Johns Hopkins University data shows.

The variant has since spread to other countries, including the United States.

— CNBC’s Rich Mendez contributed to this report.
 
Sinkieland could be involved (indirectly?) in the entire pandemic.



Novartis moving research facility out of Singapore​

PUBLISHED OCT 5, 2016

https://www.straitstimes.com/business/economy/novartis-moving-research-facility-out-of-singapore

The NITD, which employs about 85 scientists, physicians and business professionals, was set up as a public-private partnership between Novartis and the Singapore Economic Development Board (EDB) in 2002, when the biomedical sciences industry here was in its infancy.

It was among the first to move into biomedical hub Biopolis in 2004.
 
Sinkieland could be involved (indirectly?) in the entire pandemic.



Novartis moving research facility out of Singapore​

PUBLISHED OCT 5, 2016

https://www.straitstimes.com/business/economy/novartis-moving-research-facility-out-of-singapore

Its ok..got another medical company moving in..


Novartis moving research facility out of Singapore
Logos sit above windows at Novartis AG's headquarters in Basel, Switzerland.
Logos sit above windows at Novartis AG's headquarters in Basel, Switzerland.PHOTO: BLOOMBERG

Swiss pharmaceutical giant Novartis is moving a key research facility out of Singapore.

The Novartis Institute for Tropical Diseases (NITD) will be moving to Emeryville, California, next year as part of "a broader global strategic plan", president of the Novartis Institutes for BioMedical Research James Bradner told The Straits Times.

After the move, the NITD will be located next to Novartis' infectious diseases research headquarters in Emeryville.

The move is part of Dr Bradner's first strategic plan as the company's head of research. "It's a difficult decision," said the former Harvard Medical School professor, who took on this role in March.

"Moving the NITD is really intended to empower the research through the strength of collaborative proximity," added Dr Bradner, who was in Singapore on Monday to speak to government officials and staff here about the move.

The NITD, which employs about 85 scientists, physicians and business professionals, was set up as a public-private partnership between Novartis and the Singapore Economic Development Board (EDB) in 2002, when the biomedical sciences industry here was in its infancy.

It was among the first to move into biomedical hub Biopolis in 2004.

The NITD has "accomplished a tremendous amount" in Singapore, including coming up with two new malaria drugs now in clinical development, noted Dr Bradner.

Novartis hopes to continue working with Singapore researchers in areas such as digital medicine, which applies digital technology to healthcare, for example, the use of sensors to track health indicators.

Novartis' Singapore country president Christopher Snook said the company will work with affected staff one-on-one - hopefully to apply for positions at the Emeryville facility, or transfer within the company in Singapore.

He added that Novartis is still fully committed to Singapore - it has expanded its presence here over the years and intends to continue doing so. Novartis has invested over US$1.2 billion (S$1.6 billion) in Singapore and employs more than 1,500 people here. Aside from its regional headquarters and commercial operations, it operates four production plants here making drugs and eyecare products, among other things. The EDB said it is working closely with Novartis to assist affected staff.

Ms Ho Weng Si, the EDB's director of biomedical sciences, noted that other global pharmaceutical companies are still doing research here to develop new products, and biomedical manufacturing has also grown consistently.

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A version of this article appeared in the print edition of The Straits Times on October 05, 2016, with the headline 'Novartis moving research facility out of Singapore'. Subscribe
 
I am really curious. Wat would happen if the virus was allowed to spread like the Spanish flu. Would this shit be over by now? The death rate in India for the virus is not even 1%. And those that died, they died with the virus or from the virus?

Of course it would be over. All these lockdowns did was to delay the inevitable.
 
Would the virus have mutated faster n died out like SARs?

The mutations weaken over time while the host builds resistance and the pandemic ends..... if it was a pandemic in the first place.
 
Source: https://www.mirror.co.uk/news/uk-news/triple-mutant-covid-variant-identified-24161494

Triple mutant' Covid variant identified in the UK with 'strange gene combination

Public Health England is investigating the new variant with 49 cases found so far mainly in Yorkshire and Humber while people are being told not to be alarmed by it.

By
Tim Hanlon
  • 04:06, 22 MAY 2021
  • UPDATED10:02, 22 MAY 2021

A “triple mutant” Covid variant with a “strange combination” of genes is being probed by UK virologists as England’s R rate worryingly rises to potentially over one.

There have been 49 cases found so far of the new variant mainly in Yorkshire and Humber with people being told not to be alarmed by it.


The mutant form of Covid is a “variant under investigation” but there is no evidence yet to say it is more transmissible or resistant to vaccines.

At the same time, the government has said that the Covid R rate is now somewhere between 0.9 and 1.1 which is the highest it has been since the second wave peak back in January.


Ministers have said that they will put in place any measures necessary to tackle any fresh variants.

But Greg Fell, Sheffield’s director of public health said there is no reason to think the “triple mutant variant” is more transmissible or vaccine resistant.

He said in a statement: “Please don't be alarmed, we want you to continue doing what you have been for the past year. Follow the guidance, continue to wash your hands regularly and wear a mask indoors.”

He added that where cases have been found “contact tracing and targeted testing” would be used to limit its spread, while the "strange combination of mutations" continues to be probed.

The Prime Minister's official spokesman said: 'There have been a number of variants throughout the pandemic and there will continue to be so.

0_The-Duke-Of-Cambridge-Visits-Oxford-Vaccine-Group.jpg

So far 49 cases of the new triple mutant variant have been found (Image: Getty Images)

There are three mutations of the B1617 (Indian) strain, as I think has been discussed previously, but as we do with all variants where we spot and identify them through our genomic sequencing programme, we will continue to monitor them and we will designate them as variants under investigation, and then variants of concern if we deem them to be of greater risk.

“But again, as you've seen throughout the pandemic, that's what we've done and we won't hesitate to put in measures that we think are necessary to try and tackle the transmission of any variants.”

The Office for National Statistics has estimated that it is seeing a “potential increase” in Covid cases with almost 50,000 people infected by the virus on any day last week.

But Public Health England’s weekly report found that cases had dropped in every region but the North West and in every age group bar five to nine year-olds.

Cases of the Indian variant are only surging in three areas - Bolton, Blackburn and Bedford - of the 23 hotspots which also suggests that it is not heading out of control.

Similarly, King’s College London analysis found that 2,750 people had developed Covid symptoms over the past week which is little change from the previous seven days.
Still cannot beat the current global champion covid variant - b1617 - recognized by WHO as a ’variant of concern’ globally.
 
Still cannot beat the current global champion covid variant - b1617 - recognized by WHO as a ’variant of concern’ globally.

As far as I can see there is no reason to be concerned about the variant of concern.
 
Last updated: May 23, 2021, 04:01 GMT
India
Coronavirus Cases:
26,530,132
Deaths:
299,296
Recovered:
23,425,467

India has less than 300k deaths out of a 1 billion plus popn. Talk about a a storm in a teacup. That is not even 0.1 % of the popn
 
You see see from NZ, boss. NZ so safe as compared to other countries. U so larkee, am jeylus.

It's no safer or more dangerous than any other country. It has exports like timber and dairy to keep the economy going for the time being but sooner or later it will have to open the borders and there will then be a surge of cases because there is very little immunity here.

The lucky places are states like Florida and Texas which have opened up completely without restrictions.
 
It's no safer or more dangerous than any other country. It has exports like timber and dairy to keep the economy going for the time being but sooner or later it will have to open the borders and there will then be a surge of cases because there is very little immunity here.

The lucky places are states like Florida and Texas which have opened up completely without restrictions.
Australia similar to NZ... No immunity there also.
 
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