Four core cancer types
Pfizer plans to focus on four main types of cancer: breast cancer; genitourinary cancer, which impacts urinary and genital organs or functions; thoracic cancer, such as lung, head and neck cancer; and hematology-oncology, or cancers of the blood, such as multiple myeloma and lymphomas.
Pfizer expects breast cancer's contribution to total oncology sales to drop to about 10% by 2030 from roughly 40% last year, the company's oncology commercial chief Suneet Varma said during the event.
That decline accounts for the upcoming loss of exclusivity of top-seller Ibrance, which raked in $4.75 billion in sales in 2023.
But the company said it has a handful of breast cancer drugs in development that could become "potential growth drivers" as Ibrance sales fall. That includes a certain type of treatment called atirmociclib that could potentially be more effective and easier for patients to tolerate.
Pfizer is testing the medicine as a second-line treatment for a certain type of breast cancer in a phase three trial. A second-line therapy is given when an initial treatment doesn't work or stops working.
The company also plans to start a separate late-stage trial on atirmociclib as a first treatment for the same condition in the second half of the year.