Here are summaries of the new research on the schedule:
Oral microbiome signatures as potential biomarkers for gastric cancer risk assessment, Abstract 949, will be presented Monday, May 20, at 4:15 p.m. EDT. (A press release is available upon request. Embargoed until 12:01 a.m. EDT on May 9)
Researchers analyzed bacteria samples from the mouths of 98 patients scheduled for endoscopy, including 30 known to have gastric cancer, 30 with premalignant gastric conditions and 38 healthy controls, in a study presented at Digestive Disease Week (DDW) 2024. They found distinct differences between the oral microbiomes of the healthy group compared to the cancerous and pre-cancerous patients. They also found very little difference between the samples from pre-malignant patients and those with cancer, suggesting that the changes in the microbiome may occur as soon as the stomach environment starts to undergo changes that can eventually turn into cancer. The findings suggest that oral bacteria alone could be biomarkers for risk of gastric cancer, a leading cause of cancer deaths, and that a simple oral rinse has the potential to eventually serve as a non-invasive gastric cancer screening tool.