Amlodipine is an example of a calcium channel blocker.
High blood pressure meds are categorized into : calcium channel blockers, angiotensin-converting enzyme (ACE) inhibitors, beta blockers, angiotensin II receptor blockers, renin inhibitors, diuretics, alpha blockers, alpha-beta blockers, central-acting agents, vasodilators, aldosterone antagonists, etc.
For more info on the biochemical mechanism of how each category of meds work, as well as the common side effects of each, see :
https://medshadow.org/features/heart-health-meds-risks-v-benefits/
As
SeeFartLoong said, Amlodipine does have side effects (frequency and dose dependent, the more you take, the longer you take, the higher your risk of side effects), but so do ALL the other high blood pressure meds. Depending on your medical condition(s), your doctor (all these drugs are prescription only in Singapore, so you gotta see a doctor to get these anyway, don't risk buying online illegally, the drugs may not be safe) will decide on which of these blood pressure meds to prescribe you.
For example, if you have chest pain (angina), your doctor may recommend a beta blocker, which can lower your blood pressure and also prevent your chest pain, reduce your heart rate and decrease your risk of death. If you have diabetes and high blood pressure, taking a diuretic plus an ACE inhibitor can decrease your risk of a heart attack and stroke. If you have diabetes, high blood pressure and kidney disease, you may need an ACE inhibitor or an angiotensin II receptor blocker.
However, you (
Asterix and
AhMeng) may be interested to note that Amlodipine (and all CCBs in general... Ca2+ channel blockers lah, not hokkien) has a significant advantage over all the other types of blood pressure meds, in terms of protecting against stroke and myocardial infarction (which together with kidney failure, are the adverse outcomes of high blood pressure).
http://hyper.ahajournals.org/content/50/4/e71
http://hyper.ahajournals.org/content/50/4/e72
https://www.ncbi.nlm.nih.gov/pubmed/16640170
Interestingly, and fortunately for some migraine suffers (if you suffer from chronic migraines, you know the pain can drive you suicidal), Amlodipine (and CCBs in general) have proven effective in preventing and relieving migraine headaches (which shouldn't be that surprising, as migraines and headaches are linked to abnormal blood pressure changes in the brain), at least for some types of migraines and headaches.
https://www.google.com.sg/search?q=amlodipine+for+migraines
https://migraine.com/migraine-treatment/calcium-channel-blockers-to-prevent-migraine-headaches/
A non-prescription health supplement (that you can readily obtain in any pharmacy in Singapore) that is also helpful against *both* hypertension (high blood pressure) and migraines / headaches, and indeed should be taken by everyone, is magnesium. Of course, not the reduced Mg metal itself, but the oxidized Mg2+ salts or compounds, of which the choice of counter-anion does make a difference, depending on the specific beneficial health effects you seek, as the counter-anion can function as a chelating agent / ligand affecting the hydrophilicity / lipophilicity thus promoting the Mg2+ coordination complex in crossing the blood-brain barrier, for instance, among other mechanistic factors.
Magnesium threonate has nootropic effects, magnesium glycinate has anti-migraine / anti-headache effects, and all magnesium compounds have useful anti-constipation effects (both prevention and relief).
In addition to magnesium, there are other many other helpful supplements that are worth exploring to see if they work for your particular case of hypertension (differs from person to person as hypertension is as much a symptom as it is also simultaneously a disease).
An example would be Berberine, which is more commonly used by diabetics and pre-diabetics in lowering blood glucose levels, working similarly to Metformin (diabetes med), but without the side-effects. Berberine reduces both blood glucose and blood pressure.
https://www.google.com.sg/search?q=berberine+for+blood+pressure
Check out the user reviews of each of the many blood pressure lowering supplements (including magnesium and Berberine, all sold on iHerb) :
https://sg.iherb.com/search?kw=blood+pressure
Another important matter of medical significance to explore, is that of the MTHFR (sounds like motherfucker so easy to remember, but it actually stands for MethyleneTetraHydroFolate Reductase) gene that transcribes and translates for the reductase enzyme. Various mutations on this and associated genes are common in human populations (naturally including Singaporeans), which have been linked to many medical conditions, either directly or indirectly.
https://www.google.com.sg/search?q=MTHFR+gene+mutations
Diseases associated with MTHFR gene mutations (click on links to websites) :
"
Coronary heart disease, high blood pressure, insomnia, anxiety disorders, cancer, stroke, heart disease, depression, Irritable Bowel Syndrome, miscarriages, migraines, etc"
And from another website :
"
Coronary heart disease, stroke, blood clots, cancer, dementia, depression, anxiety, bipolar disorder, etc."
You can go for genetic testing to determine your genotypes for the MTHFR and associated genes, which will support your understanding of your genetic and medical condition. MTHFR genetic conditions are discussed on health / medical forums such as Longecity and Phoenix Rising, in addition to Reddit :
https://www.google.com.sg/search?q=MTHFR+gene+longecity+phoenix+rising+forum
There are several modalities or pathways in which MTHFR gene mutations cause hypertension, which involves elevated homocysteine levels and depressed glutathione levels. This is worth educating yourself on, otherwise you're just treating the hypertension syndrome with 'Band-Aid' meds, rather than approaching the underlying MTHFR genetic condition with a whole-of-health approach (
macam PAP's 'whole-of-government' catchphrase).
https://www.google.com.sg/search?q=MTHFR+gene+high+blood+pressure
https://en.wikipedia.org/wiki/Homocysteine
In addition, as shown above in the Wikipedia biochemical chart, the MTHFR enzyme works in the Folate cycle, so supplementing with the B vitamins (especially B9, but also B1, B2, B6 and B12) is crucial in approaching MTHFR genetic conditions.
But a word of caution here, as the correct form of vitamin B9 (L-Methylfolate vs Folic Acid v Folate) required will depend on your genotype. Do not anyhow buy vitamin B9 without taking this factor into consideration.
Educate yourself :
https://www.google.com.sg/search?q=MTHFR+L-Methylfolate+vs+Folic+Acid+v+Folate
Dr Ben Lynch explains the biochemistry underlying the different forms of methylfolate, and their MTHFR link :
http://mthfr.net/l-methylfolate-methylfolate-5-mthf/2012/04/05/
Methyl-Life website compares the various commercially patented trademark forms of Methylfolate available, specifically Quatrefolic® versus Metafolin® versus Extrafolate-S® versus Magnafolate-C™ :
https://methyl-life.com/methylfolate-types/
When buying on iHerb or Amazon, read carefully the ingredients and user reviews, and note which form of methylfolate is being reviewed, and/or which form worked better for the reviewer (some of whom have had experience across forms and brands).